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Paul Giamatti as Homer Simpson


Lorraine Bracco as Marge Simpson



Jacob Kogan as Bart Simpson



AnnaSophia Robb as Lisa Simpson



Jeff Goldblum as Moe



William H. Macy as Ned Flanders



Ian McDiarmid as Mr. Burns



Allison Janney as Edna Krabappel



David Schwimmer as Rev. Lovejoy



Steve Buscemi as Dr. Nick



James Earl Jones as Dr. Hibbert



Orlando Jones as Carl



Tom Arnold as Chief Wiggum



Kevin Smith as Comic Book Guy



Benicio del Toro as Snake Jailbird



Justin Long as Squeaky Voiced Teen